INT298737

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 3
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 2.06
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (ACSBG1) cytoplasmic membrane-bounded vesicle (ACSBG1) ligase activity (ACSBG1)
lipid metabolic process (ACSBG1) cytoplasm (ACSBG1)
Anatomy Link Frequency
arm 1
ACSBG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 18 88.24 High High
Glutamate 6 69.36 Quite High
withdrawal 6 5.00 Very Low Very Low Very Low
noradrenaline 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
anticonvulsant 6 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
Dopamine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoglycemia 36 96.80 Very High Very High Very High
Apoptosis 6 93.12 High High
INFLAMMATION 24 88.24 High High
Infection 48 86.20 High High
Burns 12 84.08 Quite High
Adverse Drug Reaction 6 82.64 Quite High
Acidosis 12 77.88 Quite High
Brain Injury 84 77.48 Quite High
Critical Illness 126 77.44 Quite High
Injury 60 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The aim of the present study is to determine whether a policy of strictly controlling BG using insulin in children admitted to paediatric intensive care reduces mortality, morbidity and is cost-effective.


Spec (whether) Regulation (controlling) of BG
1) Confidence 0.00 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC2830203 Disease Relevance 0.44 Pain Relevance 0
Information will also be collected on the resources required to achieve tight BG control, in particular all medication use and the staff time involved in monitoring the patients and managing adverse events (e.g. hypoglycaemia) will be noted.
Regulation (control) of BG associated with hypoglycemia
2) Confidence 0.00 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC2830203 Disease Relevance 0.10 Pain Relevance 0
Improved clinical outcomes may arise not necessarily solely as a result of control of BG.
Regulation (control) of BG
3) Confidence 0.00 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC2830203 Disease Relevance 0.82 Pain Relevance 0.08
These economic evaluations will assess whether the costs of achieving tight BG control are justified by subsequent reductions in hospitalisation costs and/or by improvements in patient outcomes.
Spec (whether) Regulation (control) of BG
4) Confidence 0.00 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC2830203 Disease Relevance 0.12 Pain Relevance 0
An economic evaluation will assess whether the costs of achieving tight BG control are justified by subsequent reductions in hospitalisation costs.


Spec (whether) Regulation (control) of BG
5) Confidence 0.00 Published 2010 Journal BMC Pediatr Section Abstract Doc Link PMC2830203 Disease Relevance 0.15 Pain Relevance 0
This is particularly important in the TCG arm of the study which is aiming to control BG within the range 4 - 7 mmol/l which is well above the 2 mmol/l threshold for clinically important hypoglycaemia [55].
Regulation (control) of BG in arm associated with hypoglycemia
6) Confidence 0.00 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC2830203 Disease Relevance 0.43 Pain Relevance 0

General Comments

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