INT298759

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Context Info
Confidence 0.60
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.25
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ATP5A1) small molecule metabolic process (ATP5A1) transmembrane transporter activity (ATP5A1)
ATPase activity (ATP5A1) plasma membrane (ATP5A1) embryo development (ATP5A1)
Anatomy Link Frequency
tectum 2
neurons 1
heart 1
ATP5A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 12 5.00 Very Low Very Low Very Low
halothane 4 5.00 Very Low Very Low Very Low
peripheral neuropathy 4 5.00 Very Low Very Low Very Low
lidocaine 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
antiepileptic Drug 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
positron emission tomography 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mitochondrial Disorders 2 70.92 Quite High
Parkinson's Disease 8 61.92 Quite High
Body Weight 2 59.16 Quite High
Sweat Gland Disease 2 56.40 Quite High
Acid Base Imbalance 2 41.32 Quite Low
Syndrome 6 35.36 Quite Low
Muscle Disease 46 25.04 Quite Low
Arrhythmias 2 Under Development 4 21.56 Low Low
Disease 62 5.00 Very Low Very Low Very Low
Coronary Heart Disease 34 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Active regulation of mitochondrial ATPsynthase requires an intact inner mitochondrial membrane.
Regulation (regulation) of ATPsynthase
1) Confidence 0.60 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2877206 Disease Relevance 0.13 Pain Relevance 0
In contrast, bilateral laser ablation of the zebrafish opticum tectum did not alter the OMR [15].
Neg (not) Regulation (alter) of OMR in tectum
2) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2830482 Disease Relevance 0 Pain Relevance 0
The mitochondrial ATPsynthase has been shown to be actively regulated both in heart [136] and in skeletal muscle [137].
Regulation (regulated) of ATPsynthase in heart
3) Confidence 0.26 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2877206 Disease Relevance 0.12 Pain Relevance 0
Due to the quite different threshold of the OMR compared to thresholds of direction-selective neurons and the OKR we presume that direction-selective neurons of the goldfish APT are not directly responsible for the OMR.
Neg (not) Regulation (responsible) of OMR in neurons
4) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2830482 Disease Relevance 0 Pain Relevance 0
Former lesion studies of the tectum opticum indicated an involvement of this structure in the OMR [14].
Regulation (involvement) of OMR in tectum opticum
5) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2830482 Disease Relevance 0 Pain Relevance 0

General Comments

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