INT298814

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Context Info
Confidence 0.45
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.80
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
WAT 1
TUSC5 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 48 95.28 Very High Very High Very High
Potency 4 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 276 99.84 Very High Very High Very High
Diabetes Mellitus 20 88.40 High High
Cancer 10 84.16 Quite High
Liver Cancer 6 5.00 Very Low Very Low Very Low
Retinoblastoma 2 5.00 Very Low Very Low Very Low
Insulin Resistance 2 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Lung Cancer 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using a subset of patients for whom archived WAT was available for measurement of Tusc5 protein abundance, consistent with the mRNA results there was large person-to-person variability in Tusc5 expression and no effect of pioglitazone treatment on Tusc5 protein levels when comparing pre- and post-treatment WAT (Supplementary Figure 2).
Neg (no) Regulation (effect) of Tusc5 protein associated with obesity
1) Confidence 0.45 Published 2009 Journal PPAR Research Section Body Doc Link PMC2830574 Disease Relevance 0.59 Pain Relevance 0.03
However, the regulation of Tusc5 in WAT and its potential association with obesity phenotypes remain unclear.
Regulation (regulation) of Tusc5 in WAT associated with obesity
2) Confidence 0.27 Published 2009 Journal PPAR Research Section Abstract Doc Link PMC2830574 Disease Relevance 1.22 Pain Relevance 0.05

General Comments

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