INT298854

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lysosome (LAMP2, RAB7A) Golgi apparatus (RAB7A) plasma membrane (LAMP2)
GTPase activity (RAB7A)
LAMP2 (Homo sapiens)
RAB7A (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 5 5.44 Low Low
Pain 3 5.00 Very Low Very Low Very Low
Congenital analgesia 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 76 100.00 Very High Very High Very High
Charcot Marie Tooth Disease 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low
Mouth Disease 2 5.00 Very Low Very Low Very Low
Ulcers 1 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Muscle Weakness 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Surprisingly, despite evidence of unregulated activation, Rab7 disease mutants have normal subcellular localization and associate normally with LAMP2 (Fig. 5B) and LysoTracker Red (data not shown).
LAMP2 Binding (associate) of Rab7 associated with disease
1) Confidence 0.16 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830827 Disease Relevance 0.56 Pain Relevance 0

General Comments

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