INT298906

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (RAB7A) GTPase activity (RAB7A) lysosome (RAB7A)
RAB7A (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Congenital analgesia 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurological Disease 2 98.64 Very High Very High Very High
Paraplegia 1 98.12 Very High Very High Very High
Choroideremia 1 97.36 Very High Very High Very High
Intellectual Impairment 1 95.80 Very High Very High Very High
Motor Neuron Diseases 1 95.40 Very High Very High Very High
Atrophic Muscular Disorders 1 94.00 High High
Disease 76 91.40 High High
Spinocerebellar Ataxia Type 2 1 83.84 Quite High
Syndrome 2 77.92 Quite High
Neurodegenerative Disease 4 49.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, mutations in previously known Rab7 interactors have been implicated in multiple neurological diseases: REP-1 in choroideremia (44,45), GDI in X-linked mental retardation (46), p150glued in distal spinobulbar muscular atrophy (47), ?
Negative_regulation (known) of Rab7 Binding (interactors) of associated with atrophic muscular disorders, intellectual impairment, neurological disease and choroideremia
1) Confidence 0.40 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830827 Disease Relevance 0.99 Pain Relevance 0

General Comments

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