INT298913

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (RAB7A) GTPase activity (RAB7A) lysosome (RAB7A)
RAB7A (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 6 49.20 Quite Low
Demyelination 2 25.44 Quite Low
Peripheral nervous system 2 10.68 Low Low
imagery 10 5.00 Very Low Very Low Very Low
Congenital analgesia 2 5.00 Very Low Very Low Very Low
Nerve growth factor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 152 96.08 Very High Very High Very High
Muscle Weakness 2 59.04 Quite High
Neuropathic Pain 2 56.56 Quite High
Amputation 2 52.56 Quite High
Congenital Anomalies 2 51.24 Quite High
Ulcers 2 50.72 Quite High
Pain 8 49.20 Quite Low
Mouth Disease 4 45.48 Quite Low
Charcot Marie Tooth Disease 12 44.92 Quite Low
Demyelinating Disease 2 25.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unregulated Rab7 cycling and accumulation of activated Rab7
Regulation (Unregulated) of Positive_regulation (accumulation) of Rab7
1) Confidence 0.42 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830827 Disease Relevance 0.54 Pain Relevance 0
We report that misregulation of Rab7 activation results in an increase in the active fraction of Rab7 and abnormal retention on target membranes.
Regulation (misregulation) of Positive_regulation (increase) of Rab7
2) Confidence 0.42 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830827 Disease Relevance 0.58 Pain Relevance 0

General Comments

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