INT298981

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ikbkb) kinase activity (Ikbkb) cytoplasm (Ikbkb)
Ikbkb (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 23 54.08 Quite High
cytokine 23 45.16 Quite Low
Inflammation 18 5.00 Very Low Very Low Very Low
Hippocampus 8 5.00 Very Low Very Low Very Low
Spinal cord 7 5.00 Very Low Very Low Very Low
depression 7 5.00 Very Low Very Low Very Low
Multiple sclerosis 7 5.00 Very Low Very Low Very Low
Substantia nigra 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 1 98.94 Very High Very High Very High
Cancer 2 98.76 Very High Very High Very High
Hypertrophy 2 45.92 Quite Low
Neuroblastoma 2 16.64 Low Low
Disease 30 5.00 Very Low Very Low Very Low
INFLAMMATION 22 5.00 Very Low Very Low Very Low
Multiple Sclerosis 16 5.00 Very Low Very Low Very Low
Stress 11 5.00 Very Low Very Low Very Low
Depression 7 5.00 Very Low Very Low Very Low
Cognitive Disorder 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This event allows activation of the IL-1R-associated kinase (IRAK)/tumor necrosis factor receptor-associated factor 6 (TRAF6) pathway leading to nuclear translocation of the nuclear factor kappa beta (NF-?
Positive_regulation (leading) of Localization (translocation) of nuclear factor kappa beta associated with necrosis and cancer
1) Confidence 0.04 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2830964 Disease Relevance 0.20 Pain Relevance 0.03

General Comments

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