INT298985

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il18) extracellular region (Il18) cytoplasm (Il18)
Il18 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 23 94.72 High High
cytokine 23 87.04 High High
Inflammation 18 50.32 Quite High
Hippocampus 8 5.00 Very Low Very Low Very Low
Spinal cord 7 5.00 Very Low Very Low Very Low
depression 7 5.00 Very Low Very Low Very Low
Multiple sclerosis 7 5.00 Very Low Very Low Very Low
Substantia nigra 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ataxia 5 75.08 Quite High
Fever 5 73.44 Quite High
Neurodegenerative Disease 5 61.36 Quite High
Anorexia 2 55.44 Quite High
INFLAMMATION 22 50.32 Quite High
Glioma 4 28.56 Quite Low
Brain Tumor 2 26.36 Quite Low
Death 1 19.04 Low Low
Disease 30 5.00 Very Low Very Low Very Low
Multiple Sclerosis 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the intriguing peculiarities of the central role of IL-18 is that despite the constitutive expression of the receptor, the regulation of IL-18 action appears to be regulated by the existence of truncated isoforms and by the fact that under normal physiological conditions IL-18 is not easily found in the CNS.
Spec (appears) Regulation (regulated) of Regulation (regulation) of IL-18 associated with central nervous system
1) Confidence 0.26 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2830964 Disease Relevance 0.32 Pain Relevance 0.22

General Comments

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