INT299000

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il18) extracellular region (Il18) cytoplasm (Il18)
Anatomy Link Frequency
brain 2
Il18 (Mus musculus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 1 92.40 High High
Pyramidal cell 1 88.60 High High
nMDA receptor 1 73.16 Quite High
depression 7 70.76 Quite High
Glutamate receptor 1 66.32 Quite High
Hippocampus 8 47.64 Quite Low
cytokine 23 43.28 Quite Low
Thalamus 1 32.64 Quite Low
Substantia nigra 3 29.68 Quite Low
Intracerebroventricular 1 6.88 Low Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 1 88.64 High High
Depression 7 70.76 Quite High
Stress 11 66.72 Quite High
Cognitive Disorder 6 60.20 Quite High
Appetite Loss 2 41.40 Quite Low
Insulin Resistance 1 32.72 Quite Low
Metabolic Syndrome 2 31.80 Quite Low
Fever 5 24.88 Low Low
Disease 30 5.00 Very Low Very Low Very Low
INFLAMMATION 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently an ex vivo study found that LPS-induced IL-18 elevation in the brain was unable to affect LTP in the CA1 hippocampal subregion [77].
Positive_regulation (elevation) of IL-18 in brain Neg (unable) Regulation (affect) of LTP
1) Confidence 0.05 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2830964 Disease Relevance 0.35 Pain Relevance 0.20

General Comments

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