INT299004

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il18) extracellular region (Il18) cytoplasm (Il18)
Anatomy Link Frequency
microglia 1
Il18 (Mus musculus)
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 7 99.20 Very High Very High Very High
chemokine 1 99.08 Very High Very High Very High
cytokine 23 98.78 Very High Very High Very High
Inflammation 18 98.58 Very High Very High Very High
Inflammatory response 2 94.88 High High
ischemia 3 80.56 Quite High
Dorsal horn 1 75.84 Quite High
intrathecal 1 66.72 Quite High
Central nervous system 23 55.84 Quite High
Hippocampus 8 54.84 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 22 98.58 Very High Very High Very High
Viral Meningitis 1 92.44 High High
Frailty 1 90.16 High High
Nervous System Injury 3 82.16 Quite High
Cv Unclassified Under Development 2 80.56 Quite High
Hypertrophy 2 77.72 Quite High
Stress 11 75.92 Quite High
Infection 5 73.88 Quite High
Influenza Virus Infection 1 72.20 Quite High
Hypoxia 3 53.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both interleukins are capable of inducing pro-inflammatory cytokines and chemokines from human microglia and astroglia, although IL-18 seems to be more potent than IL-1?.
IL-18 Binding (potent) of IL-1 in microglia associated with chemokine, inflammation and cytokine
1) Confidence 0.04 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2830964 Disease Relevance 1.16 Pain Relevance 0.58

General Comments

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