INT299147

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ren2) extracellular space (Ren2) extracellular region (Ren2)
Ren2 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 2 34.00 Quite Low
fibrosis 23 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
cva 6 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 7 99.90 Very High Very High Very High
Pressure And Volume Under Development 37 98.68 Very High Very High Very High
Hypertension 7 98.68 Very High Very High Very High
Acute Decompensated Heart Failure (ADHF) 4 95.64 Very High Very High Very High
Myocardial Infarction 37 91.56 High High
Stress 2 90.56 High High
Dyspnea 1 83.84 Quite High
Natriuresis 5 63.28 Quite High
Stroke 49 52.04 Quite High
Sprains And Strains 4 42.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors studied homozygous Ren-2 rats that overexpress the murine Ren-2d renin gene, resulting in severe hypertension with end-organ damage [21, 22].
Positive_regulation (overexpress) of Gene_expression (overexpress) of Ren-2d associated with hypertension
1) Confidence 0.24 Published 2010 Journal Curr Heart Fail Rep Section Body Doc Link PMC2831188 Disease Relevance 0.46 Pain Relevance 0
The transgenic rat overexpressing the mouse Ren-2 gene ((TGR-mREN2)27) is important in hypertension research as, in contrast to the SHR and SHR-SP rat, it is a genetically inherited form of hypertension for which the responsible gene is known.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of Ren-2 gene associated with targeted disruption and pressure and volume under development
2) Confidence 0.05 Published 2010 Journal The Open Neurology Journal Section Body Doc Link PMC2928914 Disease Relevance 1.05 Pain Relevance 0

General Comments

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