INT299310

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (RPTOR, AKT1) cytosol (RPTOR, AKT1) cell differentiation (AKT1)
nucleoplasm (AKT1) transport (AKT1) small molecule metabolic process (AKT1)
RPTOR (Homo sapiens)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 10 79.52 Quite High
Opioid 5 79.08 Quite High
opiate 9 5.00 Very Low Very Low Very Low
mu opioid receptor 5 5.00 Very Low Very Low Very Low
Morphine 3 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
narcan 1 5.00 Very Low Very Low Very Low
Pain management 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 6 5.00 Very Low Very Low Very Low
Renal Cancer 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Anaemia 1 5.00 Very Low Very Low Very Low
Thrombocytopenia 1 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 1 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00 Very Low Very Low Very Low
Asthenia 1 5.00 Very Low Very Low Very Low
Mucositis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Akt is activated by threonine phosphorylation (T308) in the catalytic domain by PI3 kinase-dependent PDK-1 and by serine phosphorylation (S473) in the hydrophobic motif by various kinases including mTOR [13-15].
mTOR Positive_regulation (activated) of Akt
1) Confidence 0.30 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2831839 Disease Relevance 0 Pain Relevance 0.12

General Comments

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