INT299382

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.55
Pain Relevance 0

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signal transduction (RTN2) endoplasmic reticulum (RTN2) signal transducer activity (RTN2)
RTN2 (Homo sapiens)
RTN2 - L539S (2) RTN2 - G577R (1)
Pain Link Frequency Relevance Heat
Pain 9 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 30 90.52 High High
Sprains And Strains 12 55.84 Quite High
Infection 24 34.44 Quite Low
Dengue 24 33.52 Quite Low
Viral Infection 3 14.48 Low Low
Fever 24 5.00 Very Low Very Low Very Low
Togavirus Infection 15 5.00 Very Low Very Low Very Low
Arthralgia 9 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Bites And Stings 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These changes produced specific amino acid changes in FD08008 (nsP3-M394I, E2-R178H, and 6K-V31I), SD08Pan (nsP1-Q120R, nsP2-G577R, nsP2-N632S, and nsP3- D372N), FD080178 (nsP2-L539S, nsP4-P181S, C-T8A, E2-K252Q, and E1-A306V), and FD080231 (nsP2-L539S, C-T8A, and E2-K252Q) (Table 3).
Gene_expression (produced) of nsP2 (Q120R, G577R)
1) Confidence 0.15 Published 2010 Journal Virol J Section Body Doc Link PMC2831882 Disease Relevance 0.14 Pain Relevance 0
These changes produced specific amino acid changes in FD08008 (nsP3-M394I, E2-R178H, and 6K-V31I), SD08Pan (nsP1-Q120R, nsP2-G577R, nsP2-N632S, and nsP3- D372N), FD080178 (nsP2-L539S, nsP4-P181S, C-T8A, E2-K252Q, and E1-A306V), and FD080231 (nsP2-L539S, C-T8A, and E2-K252Q) (Table 3).
Gene_expression (produced) of nsP2-L539S (L539S)
2) Confidence 0.15 Published 2010 Journal Virol J Section Body Doc Link PMC2831882 Disease Relevance 0.21 Pain Relevance 0
These changes produced specific amino acid changes in FD08008 (nsP3-M394I, E2-R178H, and 6K-V31I), SD08Pan (nsP1-Q120R, nsP2-G577R, nsP2-N632S, and nsP3- D372N), FD080178 (nsP2-L539S, nsP4-P181S, C-T8A, E2-K252Q, and E1-A306V), and FD080231 (nsP2-L539S, C-T8A, and E2-K252Q) (Table 3).
Gene_expression (produced) of nsP2-L539S (L539S)
3) Confidence 0.15 Published 2010 Journal Virol J Section Body Doc Link PMC2831882 Disease Relevance 0.20 Pain Relevance 0

General Comments

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