INT299427

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Foxl2) nucleus (Foxl2) DNA binding (Foxl2)
transcription factor binding (Foxl2)
Foxl2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 5 5.00 Very Low Very Low Very Low
Dopamine 5 5.00 Very Low Very Low Very Low
adenocard 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Herpes Simplex Virus 10 76.72 Quite High
Repression 65 70.08 Quite High
Adhesions 10 61.36 Quite High
Targeted Disruption 35 5.00 Very Low Very Low Very Low
Syndrome 30 5.00 Very Low Very Low Very Low
Premature Ovarian Failure 25 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 10 5.00 Very Low Very Low Very Low
Blepharophimosis 10 5.00 Very Low Very Low Very Low
Apoptosis 10 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, due to endogenous expression of Foxl2 in KK1 cells, simple over-expression resulting from transfection of a Foxl2 expression vector may not affect levels of gene expression sufficiently to be detected efficiently by microarray analysis.
Neg (not) Spec (may) Regulation (affect) of Gene_expression (expression) of Foxl2
1) Confidence 0.37 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2831895 Disease Relevance 0.15 Pain Relevance 0
Transient transfection analyses were carried out to study the effect of Foxl2 over-expression on GnRHR gene promoter-luciferase fusion activity.
Regulation (effect) of Gene_expression (expression) of Foxl2
2) Confidence 0.26 Published 2010 Journal J Ovarian Res Section Abstract Doc Link PMC2831895 Disease Relevance 0 Pain Relevance 0
The effect of Foxl2 over-expression on the activity of the GnRHR promoter was determined by comparing the luciferase activity of the promoter in the presence of pFoxl2 (over-expression) to the activity of the promoter in the absence of Foxl2 over-expression (pcDNA 3.1).
Regulation (effect) of Gene_expression (over) of Foxl2
3) Confidence 0.26 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2831895 Disease Relevance 0.06 Pain Relevance 0
The effect of Foxl2 over-expression on the activity of the GnRHR promoter was determined by comparing the luciferase activity of the promoter in the presence of pFoxl2 (over-expression) to the activity of the promoter in the absence of Foxl2 over-expression (pcDNA 3.1).
Regulation (effect) of Gene_expression (expression) of Foxl2
4) Confidence 0.26 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2831895 Disease Relevance 0.06 Pain Relevance 0
Transient transfection analyses were carried out to study the effect of Foxl2 over-expression on GnRHR gene promoter-luciferase fusion activity.
Regulation (effect) of Gene_expression (over) of Foxl2
5) Confidence 0.26 Published 2010 Journal J Ovarian Res Section Abstract Doc Link PMC2831895 Disease Relevance 0 Pain Relevance 0

General Comments

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