INT29950

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Context Info
Confidence 0.25
First Reported 1988
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.18
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GGH) extracellular space (GGH) extracellular region (GGH)
lysosome (GGH)
GGH (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 18 100.00 Very High Very High Very High
Glutamate 1 67.20 Quite High
headache 1 60.68 Quite High
aspirin 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 18 100.00 Very High Very High Very High
Galactorrhea 3 92.72 High High
Acidophil Adenoma 1 91.72 High High
Skin Appendage Disease 1 91.36 High High
Cancer 10 90.72 High High
Mental Disorders 40 90.64 High High
Chronic Disease 22 88.84 High High
Acromegaly 1 75.00 Quite High
Colon Cancer 40 68.84 Quite High
Obesity 26 68.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum GH and PRL levels decreased to 38 and 130 ng/ml.
Negative_regulation (decreased) of GH
1) Confidence 0.25 Published 1988 Journal No Shinkei Geka Section Abstract Doc Link 2849724 Disease Relevance 0.83 Pain Relevance 0.06
Increasing age reduced quality of life in the PF, BP, GH, and VT dimensions, while manual work led to worse scores in the GH, VT and SF dimensions (p-value < 0.05).
Negative_regulation (scores) of GH associated with pain
2) Confidence 0.22 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527564 Disease Relevance 0.61 Pain Relevance 0.10
Increasing age reduced quality of life in the PF, BP, GH, and VT dimensions, while manual work led to worse scores in the GH, VT and SF dimensions (p-value < 0.05).
Negative_regulation (reduced) of GH associated with pain
3) Confidence 0.22 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527564 Disease Relevance 0.60 Pain Relevance 0.10
Gamma-glutamyl hydrolase (GGH) was downregulated 1.5-fold by the high curcumin concentration after 24 hours.
Negative_regulation (downregulated) of Gamma-glutamyl hydrolase
4) Confidence 0.16 Published 2004 Journal J Carcinog Section Body Doc Link PMC421747 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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