INT299511

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.79
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 1
Elpt (Mus musculus)
Pain Link Frequency Relevance Heat
Cannabinoid receptor 62 85.40 High High
tolerance 2 73.68 Quite High
Cannabinoid 7 51.20 Quite High
Endocannabinoid 29 50.00 Quite Low
backache 1 48.64 Quite Low
Nucleus accumbens 2 30.00 Quite Low
headache 1 17.28 Low Low
abdominal pain 1 16.48 Low Low
cannabis 13 5.00 Very Low Very Low Very Low
Central nervous system 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 5 99.90 Very High Very High Very High
Disorder Of Lipid Metabolism 4 97.76 Very High Very High Very High
Metabolic Syndrome 9 97.64 Very High Very High Very High
Body Weight 4 97.16 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

4 91.20 High High
Hypopituitarism 2 87.32 High High
Acanthosis 4 84.24 Quite High
Appetite Loss 3 78.80 Quite High
Hypertrophy 7 77.84 Quite High
Impaired Glucose Tolerance 3 74.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum leptin levels were reduced (0.9 µg/l; N 2.4–24.4, reference range for adult individuals with a BMI below the 25th percentile).
Negative_regulation (reduced) of Serum leptin
1) Confidence 0.07 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2837386 Disease Relevance 0.85 Pain Relevance 0.04
Moreover, rimonabant reverses the insulin resistance and lowered plasma leptin, insulin, and free fatty acid levels in this model of diet-induced obesity [26].
Negative_regulation (lowered) of plasma leptin in plasma associated with metabolic syndrome and insulin resistance
2) Confidence 0.01 Published 2010 Journal Diabetol Metab Syndr Section Body Doc Link PMC2832623 Disease Relevance 0.85 Pain Relevance 0.36

General Comments

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