INT299634

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (MSTN) growth (MSTN) extracellular region (MSTN)
cytoplasm (MSTN)
Anatomy Link Frequency
muscle 2
vastus lateralis 2
MSTN (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 44 5.00 Very Low Very Low Very Low
Inflammation 24 5.00 Very Low Very Low Very Low
positron emission tomography 12 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Spinal cord 6 5.00 Very Low Very Low Very Low
Action potential 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Frailty 70 95.52 Very High Very High Very High
Hypoglycemia 2 81.16 Quite High
Reprotox - General 1 2 39.52 Quite Low
Aging 26 5.00 Very Low Very Low Very Low
INFLAMMATION 24 5.00 Very Low Very Low Very Low
Injury 16 5.00 Very Low Very Low Very Low
Obesity 14 5.00 Very Low Very Low Very Low
Mobility Limitation 10 5.00 Very Low Very Low Very Low
Insulin Resistance 10 5.00 Very Low Very Low Very Low
Diabetes Mellitus 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With respect to studies in human models of muscle wasting, there is similar variance in findings, with one cross-sectional study reporting no change in myostatin expression in the vastus lateralis muscle between young and older men [56], while a similar study in women found a 56% increase in myostatin expression in the vastus lateralis [57].
Positive_regulation (increase) of Gene_expression (expression) of myostatin in vastus lateralis associated with frailty
1) Confidence 0.35 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2832869 Disease Relevance 0.27 Pain Relevance 0
In animal studies, myostatin blockade using experimental agents and other approaches appears to produce increases in muscle mass and strength in rodent models [103–105].
Positive_regulation (increases) of Gene_expression (blockade) of myostatin in muscle
2) Confidence 0.25 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2832869 Disease Relevance 0.33 Pain Relevance 0

General Comments

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