INT299762

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il2) extracellular region (Il2) plasma membrane (Cd28)
Anatomy Link Frequency
T cells 3
Cd28 (Mus musculus)
Il2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 70.44 Quite High
rheumatoid arthritis 32 50.00 Quite Low
Arthritis 4 25.88 Quite Low
abatacept 10 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 9 70.44 Quite High
Rheumatoid Arthritis 32 50.00 Quite Low
Disease 17 45.60 Quite Low
Targeted Disruption 1 26.00 Quite Low
Arthritis 2 25.88 Quite Low
Lymphoproliferative Disease 1 21.68 Low Low
Psoriasis 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Experimental Arthritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CD28 ligation of naïve T cells has been proven to be essential for IL-2 production and cell proliferation [36].
CD28 Binding (ligation) of in T cells Positive_regulation (essential) of Gene_expression (production) of IL-2 in T cells
1) Confidence 0.03 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833979 Disease Relevance 0.07 Pain Relevance 0.04

General Comments

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