INT299799

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.32
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (GATA3) anatomical structure formation involved in morphogenesis (GATA3) DNA binding (GATA3)
signal transduction (GATA3) nucleolus (GATA3) nucleus (GATA3)
GATA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 62 90.16 High High
cytokine 24 89.12 High High
rheumatoid arthritis 53 83.76 Quite High
Arthritis 13 38.04 Quite Low
tolerance 4 5.00 Very Low Very Low Very Low
psoriasis 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 5 91.68 High High
INFLAMMATION 59 90.16 High High
Infection 3 87.68 High High
Rheumatoid Arthritis 53 83.76 Quite High
Recurrence 1 82.24 Quite High
Disease 24 54.72 Quite High
Rhinitis 2 49.04 Quite Low
Autoimmune Disease 17 45.64 Quite Low
Arthritis 13 38.04 Quite Low
Diabetes Mellitus 2 37.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Most recently, a placental derived protein (placental protein 14) could be identified that inhibited Th1 immune responses and synergized with IL-4 to promote Th2 immunity by inhibiting the downmodulation of the Th2 specific transcription factor GATA-3 [36].
Negative_regulation (inhibiting) of Negative_regulation (downmodulation) of GATA-3
1) Confidence 0.09 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833981 Disease Relevance 1.32 Pain Relevance 0.47

General Comments

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