INT299861

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Context Info
Confidence 0.68
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Prox1) DNA binding (Prox1) molecular_function (Prox1)
cytoplasm (Prox1)
Anatomy Link Frequency
lens placode 2
Prox1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ketamine 6 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cataract 9 25.68 Quite Low
Capsule Opacification 18 23.28 Low Low
Overdose 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low
Hyphema 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Prox1, a divergent homeodomain protein, is expressed initially in the early lens placode and is upregulated during fiber cell differentiation [15,16].
Positive_regulation (upregulated) of Prox1 in lens placode
1) Confidence 0.68 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2834568 Disease Relevance 0 Pain Relevance 0
During rat lens regeneration, Prox1 mRNA was upregulated during the very early stages of regeneration at day 3.
Positive_regulation (upregulated) of Prox1 in lens
2) Confidence 0.68 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2834568 Disease Relevance 0 Pain Relevance 0
At that time, more Prox1 mRNA may be needed for initiation or promotion of fiber cell differentiation.
Positive_regulation (more) of Prox1
3) Confidence 0.46 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2834568 Disease Relevance 0 Pain Relevance 0

General Comments

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