INT299978

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 10
Disease Relevance 8.47
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (FTSJ3) nucleolus (FTSJ3) nucleus (FTSJ3)
Anatomy Link Frequency
heart 2
coronary artery 1
FTSJ3 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 60 100.00 Very High Very High Very High
Nicotine 40 100.00 Very High Very High Very High
Inflammation 60 97.28 Very High Very High Very High
Angina 20 92.48 High High
ischemia 40 87.44 High High
Bioavailability 20 84.56 Quite High
cytokine 10 66.72 Quite High
antagonist 10 43.76 Quite Low
depression 10 16.32 Low Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 230 99.92 Very High Very High Very High
Coronary Artery Disease 270 99.80 Very High Very High Very High
Heart Rate Under Development 30 99.60 Very High Very High Very High
Acute Coronary Syndrome 70 98.32 Very High Very High Very High
Nicotine Addiction 70 97.64 Very High Very High Very High
INFLAMMATION 60 97.28 Very High Very High Very High
Pressure And Volume Under Development 20 94.88 High High
Disease 30 92.96 High High
Cv General 3 Under Development 20 92.48 High High
Cv Unclassified Under Development 60 87.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, antioxidants including vitamin C, N-acetylcysteine and polyethylene glycol-conjugated superoxide dismutase, and polyethylene glycol-catalase have no significant effects on EPCs [28].
Neg (no) Regulation (effects) of EPCs
1) Confidence 0.07 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 0.56 Pain Relevance 0.04
Biphasic changes of the number of CD34+ cells and EPCs have been observed in patients with heart failure.
Regulation (changes) of EPCs in heart associated with myocardial infarction
2) Confidence 0.05 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 1.26 Pain Relevance 0.22
EPCs are significantly up-regulated in mild heart failure (NYHA class I-II) but their mobilization is severely depressed in patients with advanced heart failure (NYHA III-IV) irrespectively of the origin of the disease [52,53].
Regulation (regulated) of EPCs in heart associated with disease and myocardial infarction
3) Confidence 0.05 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 1.28 Pain Relevance 0.21
An inverse relationship has been found between circulating EPCs and CAD severity, independently of traditional risk factors [42] (Table 2).
Regulation (circulating) of EPCs associated with coronary artery disease
4) Confidence 0.05 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 1.23 Pain Relevance 0.03
The number of circulating CD133+ or CD34+/KDR+ EPCs and EPC function estimated by proliferation of CFU-ECs inversely correspondent with the degree of endothelial function impairment [44].
Regulation (circulating) of EPCs
5) Confidence 0.05 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 0.85 Pain Relevance 0.12
However, higher nicotine levels will have cytotoxic effects on EPCs, indicating complex effects of nicotine on EPCs [33].
Regulation (effects) of EPCs associated with nicotine
6) Confidence 0.03 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 0.85 Pain Relevance 0.19
The numbers of circulating EPCs may be significantly affected by cardiac surgery, including coronary artery bypass grafting and valve surgery.
Spec (may) Regulation (affected) of EPCs in coronary artery
7) Confidence 0.03 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 0.51 Pain Relevance 0.05
In addition to the effects of PPAR-gamma agonists on EPCs, another PPAR subtype -the PPAR agonists- has recently attracted attention.
Regulation (effects) of EPCs associated with agonist
8) Confidence 0.03 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 0.27 Pain Relevance 0.32
Serum LDL cholesterol levels, a positive family history of CAD, and age have all been shown to influence the number and migration of circulating CD34+ cells and EPCs [9].
Regulation (influence) of EPCs associated with coronary artery disease
9) Confidence 0.03 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 0.83 Pain Relevance 0
However, higher nicotine levels will have cytotoxic effects on EPCs, indicating complex effects of nicotine on EPCs [33].
Regulation (effects) of EPCs associated with nicotine
10) Confidence 0.03 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 0.83 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox