INT299988

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, IL8) extracellular region (IL6, IL8) signal transduction (IL8)
aging (IL6) intracellular (IL8)
Anatomy Link Frequency
keratinocytes 2
IL6 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 50 90.04 High High
Osteoarthritis 3 88.72 High High
rheumatoid arthritis 3 86.80 High High
Eae 14 85.04 High High
cytokine 5 82.68 Quite High
agonist 4 82.00 Quite High
qutenza 1 81.36 Quite High
Inflammation 18 80.72 Quite High
Pain 30 75.44 Quite High
b2 receptor 11 60.00 Quite High
Disease Link Frequency Relevance Heat
Osteoarthritis 3 88.72 High High
Rheumatoid Arthritis 3 86.80 High High
Inflammatory Pain 13 85.04 High High
INFLAMMATION 19 80.72 Quite High
Pain 32 75.44 Quite High
Injury 32 9.20 Low Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of the TRPV1 results in an increased release of IL-8 and PGE2 by epidermal keratinocytes [49], IL-6 [53] and IL-8 [54] by human bronchial epithelial cells and IL-6 by dental pulp fibroblast [52].
IL-6 Positive_regulation (increased) of Localization (release) of IL-8 in keratinocytes
1) Confidence 0.05 Published 2010 Journal Mol Pain Section Body Doc Link PMC2834653 Disease Relevance 0.81 Pain Relevance 0.94

General Comments

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