INT300081

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.13
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (JAK2, TYK2) cytoskeleton (JAK2, TYK2) nucleus (JAK2, TYK2)
cytoplasm (JAK2, TYK2) cell differentiation (JAK2) signal transduction (JAK2)
JAK2 (Homo sapiens)
TYK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
drug abuse 3 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
opioid receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis C Virus Infection 117 91.16 High High
Opiate Addiction 79 75.68 Quite High
Infection 64 72.96 Quite High
Disease 3 5.00 Very Low Very Low Very Low
Drug Dependence 3 5.00 Very Low Very Low Very Low
Liver Disease 2 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 5.00 Very Low Very Low Very Low
Viral Infection 2 5.00 Very Low Very Low Very Low
Hepatitis 2 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The binding brings the associated Jaks (Jak2 and Tyk2) phosphorylation and the activated signals are then transduced to STATs, which become phosphorylated and form dimers (Fig. 9).
Jak2 Binding (associated) of Tyk2
1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2834757 Disease Relevance 1.13 Pain Relevance 0

General Comments

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