INT300192

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (APOA1, HSD11B1) endoplasmic reticulum (HSD11B1) enzyme binding (APOA1)
transmembrane transport (APOA1) lipid metabolic process (APOA1) extracellular space (APOA1)
APOA1 (Homo sapiens)
HSD11B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 85.04 High High
Pain 2 41.84 Quite Low
headache 2 24.04 Low Low
backache 1 23.28 Low Low
abdominal pain 1 22.40 Low Low
Bile 16 16.60 Low Low
cva 7 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 150 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 12 99.04 Very High Very High Very High
Pressure And Volume Under Development 4 89.56 High High
Insulin Resistance 1 74.56 Quite High
Rhabdomyolysis 3 44.44 Quite Low
Muscle Disease 5 43.72 Quite Low
Myalgia 4 41.84 Quite Low
Obesity 2 41.12 Quite Low
Hepatic Insufficiency 1 36.48 Quite Low
Liver Disease 4 29.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of ApoAI or infusion of ApoA-I in animal models increases HDL-C levels and decreases atherosclerosis.
Gene_expression (Overexpression) of ApoA-I Positive_regulation (increases) of HDL associated with increased venous pressure under development and disorder of lipid metabolism
1) Confidence 0.16 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2835557 Disease Relevance 1.08 Pain Relevance 0.08

General Comments

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