INT300196

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.01
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CHDH) small molecule metabolic process (HSD11B1) oxidoreductase activity (HSD11B1)
endoplasmic reticulum (HSD11B1)
HSD11B1 (Homo sapiens)
CHDH (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 6 46.76 Quite Low
Bile 48 5.00 Very Low Very Low Very Low
cva 21 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
nud 6 5.00 Very Low Very Low Very Low
aspirin 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
pruritus 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 450 100.00 Very High Very High Very High
Coronary Artery Disease 246 100.00 Very High Very High Very High
Cardiovascular Disease 48 97.72 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

45 95.60 Very High Very High Very High
Death 36 93.64 High High
Diabetes Mellitus 15 89.88 High High
Pressure And Volume Under Development 12 88.52 High High
Obesity 6 62.56 Quite High
Hyperlipidemia 27 47.60 Quite Low
Insulin Resistance 3 46.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to several clinical trials, a 1% increase in HDL-C is associated with a 0.7%–3% decrease in CHD events.
HDL Binding (associated) of CHD associated with coronary artery disease and disorder of lipid metabolism
1) Confidence 0.07 Published 2010 Journal Vascular Health and Risk Management Section Abstract Doc Link PMC2835557 Disease Relevance 0.89 Pain Relevance 0
Changes in HDL-C and LDL-C were associated with CHD incidence in the treatment group while changes in TG were not.
HDL Binding (associated) of CHD associated with coronary artery disease and disorder of lipid metabolism
2) Confidence 0.07 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2835557 Disease Relevance 1.59 Pain Relevance 0
We now know that high LDL-C levels are associated with increased risk of CHD, and high HDL-C levels are associated with reduced risk of CHD.
HDL Binding (associated) of CHD associated with coronary artery disease and disorder of lipid metabolism
3) Confidence 0.07 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2835557 Disease Relevance 1.43 Pain Relevance 0

General Comments

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