INT300223

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Context Info
Confidence 0.58
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.26
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (ABCG1) small molecule metabolic process (ABCG1) Golgi apparatus (ABCG1)
endoplasmic reticulum (ABCG1) intracellular (ABCG1) transmembrane transport (ABCG1)
Anatomy Link Frequency
macrophage 1
ABCG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 98.36 Very High Very High Very High
deep brain stimulation 57 98.32 Very High Very High Very High
Thalamus 31 87.04 High High
Inflammation 20 50.00 Quite Low
Serotonin 2 49.52 Quite Low
Dopamine 8 25.52 Quite Low
Pain 2 21.48 Low Low
Substantia nigra 4 21.04 Low Low
Bile 16 5.00 Very Low Very Low Very Low
cva 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 75 96.64 Very High Very High Very High
Insulin Resistance 1 96.12 Very High Very High Very High
Disorder Of Lipid Metabolism 150 93.20 High High
Increased Venous Pressure Under Development 12 84.24 Quite High
Obesity 4 77.76 Quite High
Pressure And Volume Under Development 4 69.20 Quite High
Parkinson's Disease 26 68.64 Quite High
Poisoning 1 66.40 Quite High
INFLAMMATION 24 50.00 Quite Low
Stress 12 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of the transporter ATP-binding cassette, sub-family G (WHITE), member 2 (ABCG2) also was gradually downregulated during cessation of milking, supporting its role as candidate gene for milk production traits.26 The reduction in mRNA expression of lipogenic enzymes was likely associated with a decrease in activity as shown recently for ACACA and FASN.7 Recent work with cows under a reduced milking frequency protocol27 also found downregulation of beta casein (CSN2), kappa casein (CSN3), and LALBA as well as several lipogenic genes.
Gene_expression (expression) of ATP-binding cassette, sub-family G
1) Confidence 0.58 Published 2010 Journal Bioinform Biol Insights Section Body Doc Link PMC2964046 Disease Relevance 0.06 Pain Relevance 0
PPAR agonists have been postulated to increase macrophage cholesterol efflux through increased levels of ABCA1 and ABCG1.
Gene_expression (levels) of ABCG1 in macrophage associated with agonist
2) Confidence 0.41 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2835557 Disease Relevance 0.97 Pain Relevance 0.09
The contribution of China White
Gene_expression (contribution) of White
3) Confidence 0.07 Published 2010 Journal Philosophical transactions. Series A, Mathematical, physical, and engineering sciences Section Body Doc Link PMC2944387 Disease Relevance 0.23 Pain Relevance 0.20

General Comments

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