INT30024

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Context Info
Confidence 0.50
First Reported 1988
Last Reported 1998
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 9
Disease Relevance 0.19
Pain Relevance 3.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Odc1) lyase activity (Odc1)
Anatomy Link Frequency
cardiomyocytes 7
immune cells 5
adult central nervous system 2
Odc1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 11 99.92 Very High Very High Very High
opioid receptor 15 99.64 Very High Very High Very High
Central nervous system 1 99.44 Very High Very High Very High
agonist 16 99.00 Very High Very High Very High
Enkephalin 8 93.20 High High
Hippocampus 1 89.36 High High
antagonist 16 81.16 Quite High
narcan 3 80.04 Quite High
opiate 1 79.20 Quite High
MU agonist 7 46.32 Quite Low
Disease Link Frequency Relevance Heat
Bordatella Infection 7 72.56 Quite High
Convulsion 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ability of natural and synthetic opioids to modulate the induction of ornithine decarboxylase (ODC) was investigated in immune cells and cardiomyocytes in culture.
Regulation (modulate) of Positive_regulation (induction) of ODC in cardiomyocytes associated with opioid
1) Confidence 0.50 Published 1998 Journal Mol. Cell. Biochem. Section Abstract Doc Link 9746211 Disease Relevance 0 Pain Relevance 0.31
However the drug did not affect ODC induced by other stimuli.
Neg (not) Regulation (affect) of Neg (not) Positive_regulation (induced) of ODC
2) Confidence 0.50 Published 1998 Journal Mol. Cell. Biochem. Section Abstract Doc Link 9746211 Disease Relevance 0.07 Pain Relevance 0.38
The ability of natural and synthetic opioids to modulate the induction of ornithine decarboxylase (ODC) was investigated in immune cells and cardiomyocytes in culture.
Regulation (modulate) of Positive_regulation (induction) of ornithine decarboxylase in cardiomyocytes associated with opioid
3) Confidence 0.37 Published 1998 Journal Mol. Cell. Biochem. Section Abstract Doc Link 9746211 Disease Relevance 0 Pain Relevance 0.31
These results provide the first description of ODC induction in an in vitro preparation of adult brain tissue and indicate that the hippocampal slice preparation could be used to study the molecular mechanisms which regulate the expression and activity of ODC in the adult central nervous system.
Regulation (regulate) of Positive_regulation (activity) of ODC in adult central nervous system associated with central nervous system
4) Confidence 0.27 Published 1988 Journal Brain Res. Section Abstract Doc Link 2852984 Disease Relevance 0 Pain Relevance 0.41
Modulation of the induction of ornithine decarboxylase by some opioid receptor agonists in immune cells and cardiomyocytes.
Regulation (Modulation) of Positive_regulation (induction) of ornithine decarboxylase in immune cells associated with agonist and opioid receptor
5) Confidence 0.22 Published 1998 Journal Mol. Cell. Biochem. Section Title Doc Link 9746211 Disease Relevance 0.06 Pain Relevance 0.39
The ability of natural and synthetic opioids to modulate the induction of ornithine decarboxylase (ODC) was investigated in immune cells and cardiomyocytes in culture.
Regulation (modulate) of in immune cells Positive_regulation (induction) of ODC in cardiomyocytes associated with opioid
6) Confidence 0.17 Published 1998 Journal Mol. Cell. Biochem. Section Abstract Doc Link 9746211 Disease Relevance 0 Pain Relevance 0.31
The ability of natural and synthetic opioids to modulate the induction of ornithine decarboxylase (ODC) was investigated in immune cells and cardiomyocytes in culture.
Regulation (modulate) of in immune cells Positive_regulation (induction) of ornithine decarboxylase in cardiomyocytes associated with opioid
7) Confidence 0.12 Published 1998 Journal Mol. Cell. Biochem. Section Abstract Doc Link 9746211 Disease Relevance 0 Pain Relevance 0.31
None of several other opioid ligands tested had significant effects on ODC induction.
Regulation (effects) of Positive_regulation (induction) of ODC associated with opioid
8) Confidence 0.08 Published 1996 Journal Biochim. Biophys. Acta Section Abstract Doc Link 8664348 Disease Relevance 0 Pain Relevance 0.37
Modulation of the induction of ornithine decarboxylase by some opioid receptor agonists in immune cells and cardiomyocytes.
Regulation (Modulation) of in cardiomyocytes Positive_regulation (induction) of ornithine decarboxylase in immune cells associated with agonist and opioid receptor
9) Confidence 0.07 Published 1998 Journal Mol. Cell. Biochem. Section Title Doc Link 9746211 Disease Relevance 0.06 Pain Relevance 0.39

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