INT300267

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (LAT2) intracellular (LAT2)
Anatomy Link Frequency
macrophages 1
monocytes 1
fibroblasts 1
LAT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 9 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
antidepressant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Constipation 30 85.44 High High
Diarrhoea 4 75.52 Quite High
Pulmonary Alveolar Proteinosis 105 5.00 Very Low Very Low Very Low
Respiratory Failure 15 5.00 Very Low Very Low Very Low
Pneumothorax 12 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Renal Disease 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Anaemia 3 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subjects draw up a questionnaire on defecation habits (frequency of defecation, amount and state of stool), and we collected fecal samples from the subjects both before entering and after ending the trial, to investigate LAB levels and inhibition of harmful enzyme activities.
Spec (investigate) Negative_regulation (inhibition) of LAB
1) Confidence 0.25 Published 2010 Journal Nutr J Section Abstract Doc Link PMC2835640 Disease Relevance 0.44 Pain Relevance 0
To assess if a different pattern of expression of SLC7A7/y+LAT1 and SLC7A6/y+LAT2 in LPI monocytes, macrophages and fibroblasts may justify the different transport phenotype of these cells, the expression of both genes was evaluated as number of mRNA molecules.
Negative_regulation (pattern) of LAT2 in monocytes
2) Confidence 0.21 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2999609 Disease Relevance 0 Pain Relevance 0
To assess if a different pattern of expression of SLC7A7/y+LAT1 and SLC7A6/y+LAT2 in LPI monocytes, macrophages and fibroblasts may justify the different transport phenotype of these cells, the expression of both genes was evaluated as number of mRNA molecules.
Negative_regulation (pattern) of LAT2 in fibroblasts
3) Confidence 0.07 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2999609 Disease Relevance 0 Pain Relevance 0
To assess if a different pattern of expression of SLC7A7/y+LAT1 and SLC7A6/y+LAT2 in LPI monocytes, macrophages and fibroblasts may justify the different transport phenotype of these cells, the expression of both genes was evaluated as number of mRNA molecules.
Negative_regulation (pattern) of LAT2 in macrophages
4) Confidence 0.07 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2999609 Disease Relevance 0 Pain Relevance 0

General Comments

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