INT300285

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.86
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Foxo3) nucleus (Foxo3) embryo development (Foxo3)
DNA binding (Foxo3) transcription factor binding (Foxo3) response to stress (Foxo3)
Anatomy Link Frequency
myocardium 2
Foxo3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 14 92.96 High High
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Perioperative pain 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 55 95.92 Very High Very High Very High
Apoptosis 40 94.48 High High
Fibrosis 12 92.96 High High
Hypertrophy 14 91.64 High High
Myocardial Infarction 78 88.56 High High
Cardiovascular Disorder Under Development 2 75.52 Quite High
Coronary Heart Disease 10 74.96 Quite High
Stress 8 48.20 Quite Low
Cicatrix 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the GK rat myocardium, Akt- and FOXO3a-phosphorylation was decreased and nuclear localization of FOXO3a was increased concomitantly with increased PTEN protein expression.
Positive_regulation (increased) of Localization (localization) of FOXO3a in myocardium
1) Confidence 0.38 Published 2010 Journal Cardiovasc Diabetol Section Abstract Doc Link PMC2835668 Disease Relevance 1.86 Pain Relevance 0.12

General Comments

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