INT300294

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.55
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gk) histone binding (Gk) nucleus (Gk)
carbohydrate metabolic process (Gk) cytoplasm (Gk)
Anatomy Link Frequency
aorta 2
Gk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Bioavailability 4 71.76 Quite High
fibrosis 28 43.48 Quite Low
anesthesia 7 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Perioperative pain 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Buprenorphine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 157 100.00 Very High Very High Very High
Myocardial Infarction 156 100.00 Very High Very High Very High
Hyperglycemia 17 75.36 Quite High
Coronary Artery Disease 6 68.60 Quite High
Apoptosis 81 67.04 Quite High
Coronary Heart Disease 21 66.48 Quite High
Cardiovascular Disease 2 57.48 Quite High
Fibrosis 24 43.48 Quite Low
Hypertrophy 28 22.36 Low Low
Acute Decompensated Heart Failure (ADHF) 2 5.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
6 mol/L acetylcholine-induced relaxation of the carotid artery was significantly reduced in GK rats compared with age matched Wistar (GK; 41±7%, Wistar; 100±5%) and measurements in the aorta showed a similar trend (p?
Negative_regulation (reduced) of Gene_expression (rats) of GK in aorta
1) Confidence 0.14 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2909910 Disease Relevance 0.46 Pain Relevance 0.04
Increased p38 MAP kinase phosphorylation in diabetic GK rats after MI
Negative_regulation (diabetic) of Gene_expression (rats) of GK associated with diabetes mellitus and myocardial infarction
2) Confidence 0.12 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2835668 Disease Relevance 1.34 Pain Relevance 0
The phosphorylation status of Akt-regulated FOXO3a transcription factor was decreased in sham- and MI GK rats and MI Wistar rats (Figure 5C).
Negative_regulation (decreased) of Gene_expression (rats) of GK associated with myocardial infarction
3) Confidence 0.12 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2835668 Disease Relevance 1.76 Pain Relevance 0

General Comments

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