INT300305

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.25
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk14, Ctgf) cell differentiation (Ctgf) mitochondrion (Mapk14)
cell morphogenesis (Mapk14) Golgi apparatus (Ctgf) response to stress (Mapk14)
Anatomy Link Frequency
heart 2
Mapk14 (Rattus norvegicus)
Ctgf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 14 98.68 Very High Very High Very High
Inflammation 3 78.24 Quite High
anesthesia 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Perioperative pain 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disorder Under Development 2 98.68 Very High Very High Very High
Diabetes Mellitus 55 97.28 Very High Very High Very High
Fibrosis 12 88.92 High High
Coronary Heart Disease 10 88.40 High High
Myocardial Infarction 78 85.12 High High
INFLAMMATION 3 78.24 Quite High
Hypoxia 1 71.24 Quite High
Hypertrophy 14 63.80 Quite High
Apoptosis 40 62.80 Quite High
Stress 8 56.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies have indicated an increase in cardiac fibrosis in response to p38 MAPK overexpression and shown that adenoviral p38-injection into the heart increased CTGF mRNA expression [27].
p38-injection Positive_regulation (increased) of Gene_expression (expression) of CTGF mRNA in heart associated with fibrosis and cardiovascular disorder under development
1) Confidence 0.19 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2835668 Disease Relevance 1.25 Pain Relevance 0.17

General Comments

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