INT300326

Context Info Confidence 0.12 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 7 Total Number 7 Disease Relevance 0.39 Pain Relevance 0.20

Anatomy Link Frequency muscle 2 masseter 1 Atp9b (Mus musculus)

Pain Link Frequency Relevance Heat Sciatic nerve 20 81.92 Inflammation 1 56.24 Calcitonin gene-related peptide 8 44.20 anesthesia 7 5.00 Spinal cord 1 5.00 Root ganglion neuron 1 5.00

Disease Link Frequency Relevance Heat Sprains And Strains 18 98.60 INFLAMMATION 1 56.24 Body Weight 31 5.00 Hypercalcemia 6 5.00 Microphthalmia 6 5.00 Dislocations 6 5.00 Deafness 6 5.00 Bone Fracture 2 5.00 Bone Cancer 1 5.00 Ganglion Cysts 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The expression level of MyHC IIb mRNA gradually increased between 1 and 8 weeks of age.

Transcription (expression) of IIb

1) Confidence 0.12 Published 2010 Journal The Open Dentistry Journal Section Body Doc Link PMC2835863 Disease Relevance 0.07 Pain Relevance 0

Fig. (7) shows the changes in the expression of MyHC IIb mRNA in the masseter (A) and gastrocnemius (B) muscles between 1 and 8 weeks of age.

Transcription (expression) of IIb in masseter

2) Confidence 0.12 Published 2010 Journal The Open Dentistry Journal Section Body Doc Link PMC2835863 Disease Relevance 0 Pain Relevance 0

In the gastrocnemius muscle, the expression levels of MyHC IIb mRNA increased between 1 and 3 weeks of age in the +/+ mice, and between 1 and 2 weeks of age in the mi/mi mice; it remained stable thereafter in both strains.

Transcription (expression) of IIb in muscle associated with sprains and strains

3) Confidence 0.12 Published 2010 Journal The Open Dentistry Journal Section Body Doc Link PMC2835863 Disease Relevance 0.09 Pain Relevance 0

No significant difference in the expression of MyHC IIa and IIb mRNAs in the masseter muscle was found between the mi/mi and +/+.

Transcription (expression) of IIb in muscle

4) Confidence 0.12 Published 2010 Journal The Open Dentistry Journal Section Abstract Doc Link PMC2835863 Disease Relevance 0 Pain Relevance 0

No significant difference in the expression levels of MyHC IIb mRNA was found between the mi/mi and +/+ mice at any time point.

Transcription (expression) of IIb

5) Confidence 0.12 Published 2010 Journal The Open Dentistry Journal Section Body Doc Link PMC2835863 Disease Relevance 0.08 Pain Relevance 0

No significant difference in the expression levels of MyHC IIb mRNA was found between the mi/mi and +/+ mice at any time point.

Transcription (expression) of IIb

6) Confidence 0.12 Published 2010 Journal The Open Dentistry Journal Section Body Doc Link PMC2835863 Disease Relevance 0.10 Pain Relevance 0

MHC IIb mRNA was not detected in the ipsilateral femora, ipsilateral tibiae, or bone marrows from ipsilateral femora and tibiae (n?

Neg (not) Transcription (detected) of IIb

7) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2946924 Disease Relevance 0.06 Pain Relevance 0.20

General Comments

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