INT300363

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.90
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (MARCKS) plasma membrane (MARCKS) cytoplasm (MARCKS)
MARCKS (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 67.80 Quite High
Chronic pancreatitis 2 22.60 Low Low
Bile 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 3 11 99.12 Very High Very High Very High
Prostate Cancer 20 99.02 Very High Very High Very High
Apoptosis 5 97.94 Very High Very High Very High
Cancer 169 92.72 High High
Disease 6 87.60 High High
Metastasis 4 86.48 High High
Colon Cancer 4 56.00 Quite High
Disease Progression 1 44.64 Quite Low
Colorectal Cancer 1 33.88 Quite Low
Pancreatitis 2 22.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The study suggested that miR-21 could promote apoptosis resistance, motility, and invasion in prostate cancer cells and these effects of miR-21 may be partly due to its regulation of target genes such as PDCD4, TPM1, and MARCKS.


Positive_regulation (due) of Regulation (regulation) of MARCKS associated with prostate cancer and apoptosis
1) Confidence 0.13 Published 2010 Journal Silenc Section Body Doc Link PMC2835996 Disease Relevance 1.90 Pain Relevance 0.07

General Comments

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