INT300375

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lymph node 1
bone marrow 1
MIR1-1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 4 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 16 99.84 Very High Very High Very High
Myeloid Leukemia 6 97.96 Very High Very High Very High
Metastasis 8 96.84 Very High Very High Very High
Chronic Lymphoid Leukemia 10 93.68 High High
Cancer 338 91.72 High High
Leukemia 20 88.96 High High
Pancreatic Cancer 28 72.64 Quite High
Hematologic Neoplasms 2 55.44 Quite High
Lung Cancer 18 39.12 Quite Low
Apoptosis 10 32.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another miRNA miR-9-3 is downregulated in breast cancer with either high vascular invasion or presence of lymph node metastasis [22].
Negative_regulation (downregulated) of miR in lymph node associated with breast cancer and metastasis
1) Confidence 0.42 Published 2010 Journal Silenc Section Body Doc Link PMC2835996 Disease Relevance 1.12 Pain Relevance 0
In another experiment, it has been revealed that miR-23b is repressed and miR-221, miR-222 and miR-34a are significantly upregulated in AML specimens compared to normal bone marrow and CD34+ haematopoietic progenitor cells [35].


Negative_regulation (repressed) of miR in bone marrow associated with myeloid leukemia
2) Confidence 0.42 Published 2010 Journal Silenc Section Body Doc Link PMC2835996 Disease Relevance 1.26 Pain Relevance 0

General Comments

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