INT300436

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Flt1, Kdr) nucleus (Flt1, Kdr) plasma membrane (Flt1, Kdr)
cell differentiation (Flt1) endosome (Flt1) Golgi apparatus (Flt1)
Anatomy Link Frequency
vascular endothelium 1
Flt1 (Rattus norvegicus)
Kdr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 7 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 55 95.60 Very High Very High Very High
Injury 2 55.16 Quite High
Diabetic Macular Edema 21 48.60 Quite Low
Ganglion Cysts 2 27.28 Quite Low
Age-related Macular Degeneration 7 5.00 Very Low Very Low Very Low
Cataract 3 5.00 Very Low Very Low Very Low
Blindness 3 5.00 Very Low Very Low Very Low
Retinal Diseases 2 5.00 Very Low Very Low Very Low
Fibromyalgia 2 5.00 Very Low Very Low Very Low
Ocular Hypertension 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FLT-1 on endothelial cells may function as a negative regulator of FLK-1, acting as a so-called “decoy” receptor that regulates the activity of VEGFs on vascular endothelium by sequestering VEGF-A and thus rendering it less available to bind to FLK-1 (27).
FLT-1 Negative_regulation (regulator) of FLK-1 in vascular endothelium
1) Confidence 0.35 Published 2008 Journal Diabetes Section Body Doc Link PMC2836241 Disease Relevance 0.40 Pain Relevance 0

General Comments

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