INT300542

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.68
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il17f) extracellular region (Il17f)
Anatomy Link Frequency
eosinophils 1
Il17f (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 87 99.82 Very High Very High Very High
cytokine 78 99.32 Very High Very High Very High
Inflammation 41 92.36 High High
Inflammatory response 2 68.80 Quite High
rheumatoid arthritis 54 5.00 Very Low Very Low Very Low
chemokine 7 5.00 Very Low Very Low Very Low
Crohn's disease 5 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 70 99.82 Very High Very High Very High
Asthma 104 97.84 Very High Very High Very High
INFLAMMATION 39 92.36 High High
Rhinitis 3 91.56 High High
Infection 3 89.12 High High
Eczema 1 83.32 Quite High
Disease 44 72.00 Quite High
Bacterial Respiratory Disease 2 39.40 Quite Low
Bacterial Infection 1 37.72 Quite Low
Multiple Sclerosis 8 29.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors demonstrated that IL-23 in combination with IL-17A and IL-17F promoted the production of CXCL1 and IL-8 in human eosinophils generating a strong neutrophilotactic signal, whereas IL-23 together with IL-17F alone induced the production of IL-1?
IL-17F Binding (combination) of in eosinophils
1) Confidence 0.05 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.81 Pain Relevance 0.05
Further studies are needed to clarify the role of IL-17F in arthritis and the interaction of IL-17F with other Th17 cytokines.


IL-17F Binding (interaction) of associated with cytokine and arthritis
2) Confidence 0.05 Published 2010 Journal Semin Immunopathol Section Body Doc Link PMC2836464 Disease Relevance 0.86 Pain Relevance 0.46

General Comments

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