INT300546

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il23a) extracellular region (Il23a)
Anatomy Link Frequency
T cells 1
Il23a (Mus musculus)
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 33 97.92 Very High Very High Very High
Inflammation 15 77.56 Quite High
Arthritis 86 68.88 Quite High
Inflammatory response 1 42.64 Quite Low
rheumatoid arthritis 54 5.00 Very Low Very Low Very Low
Crohn's disease 5 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 7 92.12 High High
Arthropathy 4 78.04 Quite High
INFLAMMATION 12 77.56 Quite High
Arthritis 69 68.88 Quite High
Experimental Arthritis 7 46.72 Quite Low
Disease 30 35.12 Quite Low
Rheumatoid Arthritis 54 5.00 Very Low Very Low Very Low
Systemic Sclerosis 13 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 12 5.00 Very Low Very Low Very Low
Seronegative Spondarthritis 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, IL-1 signaling in T cells was required in dendritic cell-mediated Th17 cell differentiation from naïve or regulatory precursors and IL-1 synergized with IL-6 and IL-23 to regulate Th17 cell differentiation and maintain cytokine expression in effector Th17 cells [11].
IL-23 Binding (synergized) of IL-1 in T cells associated with cytokine
1) Confidence 0.01 Published 2010 Journal Semin Immunopathol Section Body Doc Link PMC2836464 Disease Relevance 0.50 Pain Relevance 0.25

General Comments

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