INT300549

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Irf4) DNA binding (Irf4) cytoplasm (Irf4)
Anatomy Link Frequency
Th17 cell 2
Il1 (Mus musculus)
Irf4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 33 98.36 Very High Very High Very High
Arthritis 86 82.00 Quite High
Inflammation 15 72.12 Quite High
Inflammatory response 1 55.76 Quite High
rheumatoid arthritis 54 5.00 Very Low Very Low Very Low
Crohn's disease 5 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 7 86.68 High High
Arthritis 69 82.00 Quite High
Arthropathy 4 72.60 Quite High
INFLAMMATION 12 72.12 Quite High
Disease 30 48.24 Quite Low
Experimental Arthritis 7 41.28 Quite Low
Infection 1 14.08 Low Low
Rheumatoid Arthritis 54 5.00 Very Low Very Low Very Low
Systemic Sclerosis 13 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-1 regulated the expression of the transcription factors IRF4 and RORgammat during Th17 cell differentiation [11].
IL-1 Regulation (regulated) of Gene_expression (expression) of IRF4 in Th17 cell
1) Confidence 0.01 Published 2010 Journal Semin Immunopathol Section Body Doc Link PMC2836464 Disease Relevance 0.63 Pain Relevance 0.33

General Comments

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