INT300580

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Adora2b) signal transducer activity (Adora2b)
Anatomy Link Frequency
neuronal 1
Adora2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
long-term potentiation 1 98.56 Very High Very High Very High
cocaine 105 89.84 High High
addiction 5 87.20 High High
adenocard 3 85.28 High High
Morphine 2 61.20 Quite High
alcohol 1 60.40 Quite High
Nicotine 1 59.36 Quite High
drug abuse 1 57.72 Quite High
Nucleus accumbens 35 50.00 Quite Low
Neuropeptide 3 47.84 Quite Low
Disease Link Frequency Relevance Heat
Drug Dependence 2 87.20 High High
Aids-related Complex 11 53.16 Quite High
Cocaine Dependence 10 5.00 Very Low Very Low Very Low
Recurrence 8 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although the mechanisms underlying these effects are unclear, Drd5 signaling is implicated in neuronal activities including long-term potentiation (LTP; [35]), and reinforcement learning [36], while both Drd5 [37] and Adora2b [38] appear to affect Ca2+ dynamics.
Spec (appear) Regulation (affect) of Adora2b in neuronal associated with long-term potentiation
1) Confidence 0.26 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2837051 Disease Relevance 0.25 Pain Relevance 0.40

General Comments

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