INT300621

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Context Info
Confidence 0.56
First Reported 2005
Last Reported 2005
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 4.63
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein binding, bridging (Men1) embryo development (Men1) DNA binding (Men1)
protein complex (Men1) cytoplasm (Men1) cytosol (Men1)
Men1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 8 99.96 Very High Very High Very High
5HT 2 99.52 Very High Very High Very High
imagery 10 92.12 High High
Somatostatin 8 49.88 Quite Low
agonist 2 43.24 Quite Low
dopamine receptor 2 42.88 Quite Low
Dopamine 2 38.56 Quite Low
tolerance 2 29.60 Quite Low
depression 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Endocrine Neoplasia Type 1 156 100.00 Very High Very High Very High
Carcinoid 28 99.92 Very High Very High Very High
Parathyroid Cancer 16 96.56 Very High Very High Very High
Cancer 80 94.64 High High
Malignant Neoplastic Disease 8 70.80 Quite High
Adrenal Cancer 4 59.40 Quite High
Adenoma 4 55.68 Quite High
Acromegaly 6 52.16 Quite High
Prolactinoma 6 41.68 Quite Low
Disease 2 31.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Carcinoid tumours in MEN1 do not release serotonin (5HT), but do produce 5-hydroxytryptophan (5-HTP), the precursor of serotonin.
Neg (not) Localization (release) of MEN1 associated with multiple endocrine neoplasia type 1, carcinoid, 5ht and serotonin
1) Confidence 0.56 Published 2005 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2837063 Disease Relevance 2.33 Pain Relevance 0.27
Aetiology of MEN1
Localization (Aetiology) of MEN1 associated with multiple endocrine neoplasia type 1
2) Confidence 0.52 Published 2005 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2837063 Disease Relevance 2.30 Pain Relevance 0.25

General Comments

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