INT300753

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL13) extracellular space (IL13) extracellular region (IL13)
plasma membrane (Cd28) cell-cell signaling (IL13) cytoplasm (IL13)
Anatomy Link Frequency
T cell 3
Cd28 (Mus musculus)
IL13 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 16 100.00 Very High Very High Very High
chemokine 1 68.52 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
colic 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 17 22.88 Low Low
Syndrome 25 5.00 Very Low Very Low Very Low
Disease 19 5.00 Very Low Very Low Very Low
Infection 16 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 9 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Autoimmune Disease 8 5.00 Very Low Very Low Very Low
General Immunology 7 5.00 Very Low Very Low Very Low
Eosinophilia 6 5.00 Very Low Very Low Very Low
Eczema 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The sequential events include induction of CD 80/86 on the B cell that engages CD28 on the T cell, leading to transcription of pivotal Th2 cytokines IL-4 and/or IL-13.
CD28 Binding (engages) of in T cell Positive_regulation (leading) of Transcription (transcription) of IL-13 in T cell associated with cytokine
1) Confidence 0.00 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2837605 Disease Relevance 0 Pain Relevance 0.17

General Comments

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