INT300859

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6, Ngf) extracellular region (Il6, Ngf) signal transduction (Ngf)
Il6 (Mus musculus)
Ngf (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 4 98.28 Very High Very High Very High
cytokine 8 81.76 Quite High
trk B 1 63.12 Quite High
Inflammation 13 19.52 Low Low
Arthritis 3 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
qutenza 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 17 97.88 Very High Very High Very High
Hematological Disease 12 97.16 Very High Very High Very High
Apoptosis 5 55.84 Quite High
Targeted Disruption 4 14.00 Low Low
Disease 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Asthma 2 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with the microarray data, IL-6 gene and protein expression increased after exposure to both NGF and BDNF as determined by real-time PCR and ELISA respectively (Figure 3C, D and Figure 4).
IL-6 gene Positive_regulation (increased) of NGF
1) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2837737 Disease Relevance 0.30 Pain Relevance 0.12

General Comments

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