INT300876

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (NTRK2) extracellular region (Bdnf) plasma membrane (NTRK2)
cytoplasmic membrane-bounded vesicle (Bdnf)
Bdnf (Mus musculus)
NTRK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
trk B 1 100.00 Very High Very High Very High
Inflammatory response 4 77.08 Quite High
Inflammation 13 60.96 Quite High
cytokine 8 60.56 Quite High
Arthritis 3 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
qutenza 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 17 76.68 Quite High
Hematological Disease 12 75.96 Quite High
Targeted Disruption 4 55.44 Quite High
Apoptosis 5 34.64 Quite Low
Disease 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Asthma 2 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Uniquely, the Trk B receptor (NTRK2) was increased by NGF, but not BDNF, with the increase reaching our threshold cut-off of three times that of untreated cells.
BDNF Positive_regulation (increased) of Trk B receptor associated with trk b
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2837737 Disease Relevance 0.27 Pain Relevance 0.15

General Comments

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