INT300891

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tgm2) mitochondrion (Tgm2) proteinaceous extracellular matrix (Tgm2)
plasma membrane (Tgm2) transferase activity, transferring acyl groups (Tgm2) cytoplasm (Tgm2)
Anatomy Link Frequency
brain 1
Atp9a (Mus musculus)
Tgm2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 27.80 Quite Low
medulla 4 17.84 Low Low
headache 2 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ataxia 44 77.44 Quite High
Celiac Disease 84 70.84 Quite High
INFLAMMATION 4 27.80 Quite Low
Autoimmune Disease 6 5.00 Very Low Very Low Very Low
Neurologic Manifestations 4 5.00 Very Low Very Low Very Low
Neurological Disease 4 5.00 Very Low Very Low Very Low
Frailty 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Identical results were obtained on mouse and monkey brain sections (data not shown) suggesting that the faint staining of class2 scFv on TG2-rich tissues (Figure 3F) is likely to relate to its poor affinity for TG2 of species other than human.
class2 scFv Spec (likely) Binding (affinity) of TG2 in brain
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2837746 Disease Relevance 0.11 Pain Relevance 0
Therefore, it is unlikely that in mice, class2 can exert its effect by reacting with TG2.
class2 Binding (reacting) of TG2
2) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2837746 Disease Relevance 0.28 Pain Relevance 0

General Comments

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