INT301081

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.16
Pain Relevance 3.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (GNAT1) signal transduction (GNAT1) plasma membrane (GNAT1)
GTPase activity (GNAT1) cytoplasm (GNAT1) signal transducer activity (GNAT1)
GNAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
spastic colon 280 98.48 Very High Very High Very High
nud 60 96.28 Very High Very High Very High
Analgesic 28 61.00 Quite High
opiate 24 58.00 Quite High
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

268 98.48 Very High Very High Very High
Dyspepsia 60 96.28 Very High Very High Very High
Flatulence 60 95.76 Very High Very High Very High
Diarrhoea 20 83.44 Quite High
Constipation 16 75.04 Quite High
Functional Bowel Disorder 28 75.00 Quite High
Achlorhydria 4 48.28 Quite Low
Nicotine Addiction 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ninety-eight patients were identified who underwent a GBT (mean age, 49 y; 78% female).
Positive_regulation (underwent) of GBT
1) Confidence 0.12 Published 2010 Journal BMC Gastroenterol Section Abstract Doc Link PMC2838757 Disease Relevance 0.44 Pain Relevance 0.54
One logical conclusion would be that GBT is more likely to be positive in a person >55 years of age who has IBS like symptoms, especially those with prominence of bloating and flatulence.


Positive_regulation (positive) of GBT associated with flatulence, spastic colon and nud
2) Confidence 0.12 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2838757 Disease Relevance 0.58 Pain Relevance 0.85
A positive GBT result was more likely in patients >55 years of age (odds ratio [OR], 3.6; 95% confidence interval [CI], 1.4-9.0) and in females (OR, 4.0; 95% CI, 1.1-14.5).
Positive_regulation (result) of GBT
3) Confidence 0.12 Published 2010 Journal BMC Gastroenterol Section Abstract Doc Link PMC2838757 Disease Relevance 0.44 Pain Relevance 0.65
One explanation could be that the patients who underwent GBT in our study could be regarded as having a higher likelihood of a positive test based on prominence of bloating and flatulence in their symptom profile.
Positive_regulation (underwent) of GBT associated with flatulence and nud
4) Confidence 0.12 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2838757 Disease Relevance 0.65 Pain Relevance 0.96

General Comments

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