INT301116

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Context Info
Confidence 0.65
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 3.89
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Tgm7) cellular_component (Tgm7) biological_process (Tgm7)
Anatomy Link Frequency
nucleus 2
lung 1
Tgm7 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 14 89.12 High High
antagonist 14 75.76 Quite High
metalloproteinase 14 5.00 Very Low Very Low Very Low
Potency 14 5.00 Very Low Very Low Very Low
cINOD 7 5.00 Very Low Very Low Very Low
alcohol 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 273 99.42 Very High Very High Very High
Cancer 602 96.04 Very High Very High Very High
Reprotox - General 1 14 95.36 Very High Very High Very High
Apoptosis 21 84.04 Quite High
Body Weight 42 81.60 Quite High
Bladder Cancer 7 63.20 Quite High
Osteogenic Sarcomas 119 50.00 Quite Low
Acidosis 14 49.92 Quite Low
Obesity 14 5.00 Very Low Very Low Very Low
Weight Loss 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
M TGZ was present during the same period, contained two morphologically different cell types; one was cuboidal in shape and the other was spindle shaped, which was characterized by cell spreading and a larger cell surface area compared with the cuboidal-shaped cells, as indicated by the magnified inserts (Figure 1A, right panel).
Gene_expression (present) of TGZ
1) Confidence 0.65 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2838820 Disease Relevance 0.21 Pain Relevance 0
Since TGZ decreased the level of p-Akt (Figure 4A and 4B), this indicates that TGZ inhibits Akt signaling in LM8 cells.
Gene_expression (decreased) of TGZ
2) Confidence 0.56 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2838820 Disease Relevance 0.43 Pain Relevance 0
All mice in the control and TGZ-treated groups possessed metastatic tumors in the lung (Figure 5E); however, the proportional area of pulmonary metastasis was markedly smaller in the TGZ group than in the control group (Figure 5F).
Gene_expression (group) of TGZ in lung associated with metastasis
3) Confidence 0.56 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2838820 Disease Relevance 1.03 Pain Relevance 0
protein in the nucleus and that TGZ decreases the expression of PPAR?
Gene_expression (nucleus) of TGZ in nucleus
4) Confidence 0.56 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2838820 Disease Relevance 0.79 Pain Relevance 0.04
protein in the nucleus and that TGZ decreases the expression of PPAR?
Gene_expression (protein) of TGZ in nucleus
5) Confidence 0.56 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2838820 Disease Relevance 0.85 Pain Relevance 0.04
One group, which was termed the TGZ group, was provided with drinking water containing 100 ?
Gene_expression (group) of TGZ
6) Confidence 0.56 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2838820 Disease Relevance 0.36 Pain Relevance 0.17
Almost all cells in the untreated cultures (i.e., TGZ was absent during the 3-day treatment period) were cuboidal in shape (Figure 1A).
Neg (absent) Gene_expression (absent) of TGZ
7) Confidence 0.50 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2838820 Disease Relevance 0.22 Pain Relevance 0

General Comments

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