INT301177

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ROS1) cell proliferation (ROS1) transport (UCP2)
mitochondrion (UCP2) small molecule metabolic process (UCP2) plasma membrane (ROS1)
UCP2 (Homo sapiens)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 34 96.24 Very High Very High Very High
Diabetes Mellitus 86 79.04 Quite High
Metabolic Syndrome 5 64.48 Quite High
Nicotine Addiction 7 64.00 Quite High
Apoptosis 1 44.48 Quite Low
Prediabetic State 3 22.96 Low Low
Cardiovascular Disease 2 21.68 Low Low
Aging 10 5.00 Very Low Very Low Very Low
Coronary Artery Disease 8 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Decreased UCP2 expression results in increased ROS production, in vitro [19], while animal studies have shown that absence of UCP2 causes higher oxidative stress [20].
Gene_expression (expression) of UCP2 Positive_regulation (results) of Gene_expression (production) of ROS associated with stress
1) Confidence 0.32 Published 2010 Journal Atherosclerosis Section Body Doc Link PMC2839074 Disease Relevance 0.98 Pain Relevance 0

General Comments

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