INT3012

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Context Info
Confidence 0.49
First Reported 1977
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.98
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

trm (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 1 91.72 High High
Desipramine 1 89.88 High High
midbrain 1 77.84 Quite High
cva 1 51.12 Quite High
Arthritis 15 5.00 Very Low Very Low Very Low
rheumatoid arthritis 12 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diffuse Scleroderma 11 99.34 Very High Very High Very High
Systemic Lupus Erythematosus 21 90.84 High High
Disease 28 90.52 High High
Hypertension 1 70.52 Quite High
Toxicity 2 62.80 Quite High
Autoimmune Disease 52 56.92 Quite High
Cv General 3 Under Development 1 51.12 Quite High
Cytomegalovirus Infection 2 50.44 Quite High
Sepsis 2 49.36 Quite Low
Death 1 48.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest a role for TRM in synaptic transmission mechanisms occurring in the nigrostriatal system, a function which could be regulated by a number of substances representing some of the major chemical classes of centrally active drugs (CD).
Positive_regulation (role) of TRM
1) Confidence 0.49 Published 1977 Journal Biol. Psychiatry Section Abstract Doc Link 588646 Disease Relevance 0 Pain Relevance 0.18
A similar observation was made for SSc where nonmyeloablative regimens had a TRM of less than 4% in contrast to 23% for myeloablative conditioning with TBI, with similar efficacy [21,25,26].
Positive_regulation (had) of TRM associated with diffuse scleroderma
2) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592775 Disease Relevance 0.98 Pain Relevance 0.03

General Comments

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