INT301207

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Mir19b-2 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 112 98.68 Very High Very High Very High
Cancer 14 97.72 Very High Very High Very High
Myeloproliferative Disorder 44 95.24 Very High Very High Very High
Splenomegaly 2 75.20 Quite High
Lymphatic System Cancer 2 57.04 Quite High
Targeted Disruption 4 54.32 Quite High
Hematological Disease 12 40.16 Quite Low
Hyperplasia 4 35.28 Quite Low
Repression 2 25.56 Quite Low
Disease 16 18.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This effect was specific to miR-29a, as neither EMP retrovirus nor retroviruses expressing miR-29b, miR-29c, miR-24-2, or miR-27a significantly affected engraftment levels or lineage output when transduced into mouse HSC/committed progenitors (unpublished data).
Gene_expression (expressing) of miR-29b
1) Confidence 0.02 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.15 Pain Relevance 0
However, overexpression of miR-29b or miR-29c does not recapitulate the phenotype of miR-29a overexpression, indicating that miR-29a uniquely induces an MPD and AML.
Gene_expression (overexpression) of miR-29b associated with myeloproliferative disorder and myeloid leukemia
2) Confidence 0.02 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.90 Pain Relevance 0

General Comments

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