INT301212

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Maea) plasma membrane (Maea) cytoskeleton (Maea)
nucleus (Maea) cell cycle (Maea) cytoskeleton organization (Maea)
Anatomy Link Frequency
hematopoietic system 1
Maea (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloproliferative Disorder 44 93.16 High High
Splenomegaly 2 72.32 Quite High
Hematological Disease 12 37.28 Quite Low
Hyperplasia 4 32.40 Quite Low
Myeloid Leukemia 112 19.96 Low Low
Leukemia 34 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low
Cancer 14 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This effect was specific to miR-29a, as neither EMP retrovirus nor retroviruses expressing miR-29b, miR-29c, miR-24-2, or miR-27a significantly affected engraftment levels or lineage output when transduced into mouse HSC/committed progenitors (unpublished data).
Neg (neither) Gene_expression (retrovirus) of EMP
1) Confidence 0.05 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.14 Pain Relevance 0
To assess miR-29a function in the hematopoietic system, we transduced mouse BM cells enriched for HSC/progenitor cells with mouse miR-29a or empty control MSCV-based GFP-expressing retrovirus (EMP).
Gene_expression (expressing) of EMP in hematopoietic system
2) Confidence 0.04 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.09 Pain Relevance 0

General Comments

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